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Targeted Next-generation Sequencing for Respiratory Infection Pathogen

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Product Introduction

tNGS, also referred to as targeted next-generation sequencing , is an advanced sequencing technology that utilizes targeted capture. This approach involves enriching the genome of specific pathogenic microbes through multiplex PCR before sequencing. Subsequently, high throughput sequencing is performed, and the obtained data are compared with a reference database to determine the presence of pathogenic microbial species within the sample. Due to its practicality and efficiency, tNGS is increasingly used in clinical diagnostics.

Product Features

Comprehensive :Covers common respiratory tract infection pathogens, including bacteria, fungi, DNA/RNA viruses, mycobacteria tuberoulosis, special pathogens, and antimicrobial resistance genes. And DNA + RNA can be detected at the same time in one process.

Fast :Self-propelled sequencing platform ensures the ultimate delivery, and the whole process from receiving qualified samples to issuing report takes 8 hours.

Convenient :It is suitable for a variety of sample types such as bronchoalveolar lavage fluid, sputum, or throat swabs.

Economical and reliable :Only the specific amplified fragment needs to be detected, reducing the time and cost of assays, while improving the stability and reproducibility of data processing results.

Applicable people

High risk group of acute upper respiratory tract infection

Patients with lower respiratory tract infection (especially those with critical illness and poor previous treatment effect)

Patients with suspected tuberculosis infection

Patients with chronic respiratory tract infection

Patients with immune suppression and respiratory tract infection

Clinical significance

Increase detection of complex infections and accurately locate the cause of infection

Detection of clinical rare species to assist in the diagnosis of clinical rare infections

Increase the detection of drug-resistant genes and provide precise guidance for clinical medication

Increase the detection of difficult to detect species and significantly improve the accuracy of detection

Detection Process

DNA/RNA extraction

Library construction

Sequencing

Data analysis

Report

Lead time

Delivered quickly after receiving qualified samples.8h (bitseq mode)